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The BBMRI-ERIC EOSC Node integrates Europe’s biobanks and biomolecular resources into the EOSC Federation. It provides GDPR-compliant, FAIR access to biosamples, genomic, imaging, and clinical data across ~500 biobanks in 25 countries.

The Node enables secure federated analysis environments, contributes to the European Health Data Space (EHDS2), and supports AI-driven biomedical research with multicentric validation of models and biomarker discovery.

Key objective:

To establish the BBMRI-ERIC Node as the biomedical/sensitive health data EOSC Node, enabling FAIR and secure federated access to data, GDPR-compliant analysis, and cross-border research in alignment with EHDS2.

Science areas: Biomedical and clinical research, genomics, biomarker discovery, personalised medicine, oncology, population health, One Health.

FAIR data

The BBMRI-ERIC EOSC Node makes FAIR data from ~500 biobanks: genomics, imaging, clinical metadata. BBMRI Directory ensures findability; federated secure compute ensures accessibility and interoperability under GDPR and EHDS2 frameworks.

Scientific use cases

Multi-centric validation of AI models for prostate-cancer screening

Advances in digital pathology are transforming cancer diagnosis by enabling high-resolution imaging of tissue samples and the application of artificial intelligence (AI) for clinical decision support.

Prostate cancer, one of the most prevalent malignancies among men worldwide, represents a critical case for early and accurate diagnosis, as survival rates are strongly tied to timely detection and treatment. The objective of the multi-centric validation of AI models for prostate-cancer screening (MCVAL) use case, coordinated by the BBMRI-ERIC EOSC Node, is to create a secure environment in which AI models for prostate cancer screening can be validated using data from different hospitals. Rather than building new diagnostic systems from scratch, the project focuses on testing an existing model trained on whole-slide images and assessing how well it performs when applied to data processed elsewhere.

Other use cases

  1. Colorectal cancer prediction with explainable AI
  2. Synthetic data for computational pathology

Status

Candidate thematic EOSC Node (initial Node registration completed July 2026; Node catalogue deployment planned for August 2026).

Deliverables

The revised 2026 charter does not define a separate contractual deliverables list. Progress is tracked through the Status & Timeline and Federating Capabilities & Integration Activities sections.





Technical status

Completed

  • Federated AAI (initial Life Science AAI/eID integration demonstrated in November 2025; further eID and user-experience refinement is ongoing in 2026)
  • Existing BBMRI discovery services remain operational; EOSC Node Service Catalogue and Research Product Catalogue deployment is planned for August 2026, followed by Federation and Node Registry connection

Planned

  • Node-level service management and security coordination (planned through EOSC Mesh from September 2026)
  • Cross-node helpdesk and monitoring integration (staged implementation planned; mature in-Node support remains available)

Interactions with other EOSC Nodes


Rules of Participation

Rules of participation are based on BBMRI-ERIC AUP and Policy for Access to Biological Samples and Data. The BBMRI-ERIC policy is aligned with:

  • EOSC Federation rules
  • GDPR

Access points

Through the BBMRI Directory, Negotiator, and Sample Locator. Federated AAI ensures EOSC User access.

Federated services

  • AAI
  • Directory
  • Negotiator
  • Sample Locator

Data repositories

~500 biobanks across 25 countries

Other

  • GDPR-compliance frameworks
  • Training materials
  • EHDS2 integration

Coordinating organisation

BBMRI-ERIC

Node organisation

Coordinator

Petr Holub (BBMRI-ERIC)

Operation Manager

Andreas Türk (BBMRI-ERIC) & Kurt Majcen (BBMRI-ERIC)

Security Officer

Alexander Fürbaß

Scientific Officer

Jens Habermann

Legal/Ethics Officer

Irene Schlünder

Public Affairs

Jana Pavlic-Zupanc

Contributing organisations

  • 22 member and 3 observer countries and WHO/IARC
  • ~500 biobanks
  • Each member/observer constitutes a national node (e.g., BBMRI-AT, BBMRI-NL, BBMRI-SE, etc.)