EOSC Federation use case: Federated analysis of pathogen genomes

Today we release of the fifth in our series of short videos demonstrating how the EOSC Federation enables cross-disciplinary science.

Monitoring pathogenic outbreaks and antimicrobial resistance by establishing models for timely
cross-border health data sharing in Europe

The federated analysis of pathogen genomes science case outlines a federated, cross‑border capability for timely analysis of pathogen genomes that brings computation to the data instead of copying sensitive datasets across institutions.

The objective is to shorten time‑to‑insight for outbreak detection, source attribution, and antimicrobial‑resistance (AMR) surveillance while preserving data sovereignty and meeting European legal and ethical requirements.

Experience from COVID‑19 showed that sequencing at scale can transform public‑health decision‑making. Operationally, the effort starts with two neighbouring nodes of the EOSC Federation—the Slovakian national node providing workflows, datasets, computational infrastructure and domain expertise, and the Polish national node (via Poland’s National Science Centre (NCN) and a scientific repository service) supplying key technical support and their own datasets. Their geographical proximity make the two EOSC Nodes an ideal pair for a cross-border pilot. 

The approach demonstrates how to establish a federation of trusted sites, run harmonized workflows locally, and share only the minimum results needed for action. 


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