Result description
The data-integration platform cBioPortal is a well-established solution empowering (non-bioinformatic) researchers to query, visualize and analyze (gen)omics data – in combination with clinical and sample characteristics – in an intuitive and user-friendly manner. At the patient level, longitudinal views are available, offering additional insight into phenotypic and genotypic data over time, e.g. before, during and after cancer treatment.
In EOSC4Cancer, colorectal cancer study data are made available through cBioPortal as part of different use-cases of the project. This data includes the underlying data models and codebooks used in the original studies to facilitate harmonization efforts and development of protocols, recommendations and best practices on how to make cancer research data available compatible with this platform.
Problem addressed
Standardization, harmonization, visualization and analysis of sensitive data (cancer research data). This work will contribute towards the creation of an interoperable cancer data research ecosystem where data from controlled access data sources, e.g. EGA, can connect with cBioPortal using at least one of the virtual research environments chosen by the project (Galaxy). It will also contribute towards increasing the discoverability of data thanks to the use of individual beacon instances and the overall beacon network.
Who can use the result
A reference installation of cBioPortal, hosted by Health-RI, is made available for EOSC4Cancer use-cases (WP4). Instructions on how to set-up and host a cBioPortal instance is provided to everyone so potentially any researcher interested in working with cancer-related data can use it.Timeline
Q1/2023 The result will be available for the project partners at least until the end of the project (28/Feb/2025).How to use the result
Type of result
